PHOSPHO1 is an enzyme which is important for the proper development of our skeleton in infancy. You can learn about the function of PHOSPHO1 in the case study which comes with this dataset. Here we’ve provided you with real-life data on how expression of the Phospho1 gene changes during development of the mouse skeleton, and how much bone is present at each age. Use these data to perform your own experiment and become bone biologists!
Before we do any work in the lab, scientists have to make sure that the animals they’re working with are the correct genotype. This case study from the Easter Bush Science Outreach Centre explores what the phosphatase enzyme PHOSPHO1 has to do with bone mineralisation, and explains the process of genotyping
This paper-based PCR simulation activity to reinforce how PCR works (created by Easter Bush Science Outreach Centre) is free to download and use in your classroom.